“Biological Oxidation,   Electron Transfer chain And Oxidative  Phosphorylation- Introduction of Biological Oxidation,   Electron Transfer chain And Oxidative  Phosphorylation – ” Biochemistry Notes for Class 12 Complete Notes for Class 12

Biological Oxidation, Electron Transfer chain And  Oxidative  Phosphorylation

 

Introduction

Chemically, oxidation is defined as the removal of electrons and reduction as the gain of electrons. Thus, oxidation is always accompanied by reduction of an electron acceptor. This principle of oxidation-reduction applies equally to biochemical systems and is an important concept underlying understanding of the nature of biologic oxidation. Many biologic oxidations can take place without the participation of molecular oxygen, eg, dehydrogenations. The life of higher animals is absolutely dependent upon a supply of oxygen for respiration, the process by which cells derive energy in the form of ATP from the controlled reaction of hydrogen with oxygen to form water. In addition, molecular oxygen is incorporated into a variety of substrates by enzymes designated as oxygenases; many drugs, pollutants, and chemical carcinogens (xenobiotics) are metabolized by enzymes of this class, known as the cytochrome P450 system. Administration of oxygen can be lifesaving in the treatment of patients with respiratory or circulatory failure.

Objectives

describe biological oxidation
explain Electron transfer chain
describe oxidation phosphorylation

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