Category: Biochemistry 12
Regulation While most steps in gluconeogenesis are the reverse of those found inglycolysis, three regulated and strongly exergonic reactions are replaced with more kinetically favorable reactions. Hexokinase/glucokinase, phosphofructokinase, and …
Entering the Pathway Several non-carbohydrate carbon substrates can enter the gluconeogenesis pathway. One common substrate is lactic acid, formed during anaerobic respiration in skeletal muscle. Lactate is transported back …
Gluconeogenesis Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, and glucogenic amino acids. The vast majority …
Glycogenolysis In glycogenolysis, glycogen stored in the liver and muscles, is converted first to glucose-1- phosphate and then into glucose-6-phosphate. Two hormones which control glycogenolysis are a peptide, glucagon …
Glycogenesis Glycogenesis is the formation of glycogen from glucose. Glycogen is synthesized depending on the demand for glucose and ATP (energy). If both are present in relatively high amounts, …
Biosynthesis of Glycogen The goal of glycolysis, glycogenolysis, and the citric acid cycle is to conserve energy as ATP from the catabolism of carbohydrates. If the cells have sufficient …
Yield of ATP At this point the yield of ATP is 4 moles per mole of Glucose as it passes through the Krebs cycle. This is not much more …
Citric Acid Cycle- Kreb Cycle Under aerobic conditions the end product of glycolysis is pyruvic acid. The next step is the formation of acetyl coenzyme A (acetyl CoA) – …