Project Name : Biomedical Application of Nano-Fibers – Drug Delivery using Nano-fibers
Theme Name : Health
Nano fibers are submicron sized fibers whose diameter is 50-500 nm; nano earning 10-9 such exceptionally small fibers can only be seen and photographed by electron microscope. Nano fibers find its application in diverse fields such as filtration media, industries, nano-sensors,
protective clothing, tissues engineering scaffolds and in life sciences. Nano fibers have immense application in the field of medicine but much work is yet to be done. The desired properties of nano-fibers for its application as a drug delivery system are:
a) Protection from decomposition
b) Controlled release of drug
c) Large surface area and high porosity to facilitate diffusion
d) Local action to avoid oral or systemic drug administration thereby reducing drug dosage and non-target site toxicities.
Nano fiber Insulin oral path advantage:
i) No need to inject
ii) Can be easily removed in case of over dosage
Bandage Advantage:
i) Increased heating
ii) Drug already loaded and biodegradable
Nano fiber mosquito repellent:
i) No allergic reaction
ii) Volatile nature of loaded chemical forms a shield around body
iii) Can be worn as a band
Nano fiber oral patch to reduce tooth ache:
i) Loaded with diclofenac
ii) Local action
iii) Less dosage as it does not get reduced while reacting target site
iv) No non-target site effect (Kidney failures)
What we imagine? What we can do?
1. Nano fibers capsule – Advantages:
a) Less dose
b) Good protection
c) Small size
2. Nano booklet – when we will flip through the pages a booklet lakhs of nano fibers medicines would be there. Storage space needed for medicines would get reduced as is in the case chemist shops.
We look forward to achieve this and make our dreams come true!!!
Name of the School: Gyan Mandir Public School, Naraina Vihar, New Delhi
